Product Data Sheet
ALV-05-077-01
Catalog No. B19120
ALV-05-077-01 is a selective degrader of BCL6 and BCL6B proteins. It effectively reduces endogenous BCL6 levels in SuDHL4 cells and BCL6B levels in KYO1 cells, both of which exhibit high expression of these proteins. This compound is useful for investigating the role of BCL6 and BCL6B in hematological malignancies and provides insight into potential therapeutic strategies targeting these proteins.
Chemical Information
| Catalog Num | B19120 |
|---|---|
| M. Wt | 514.45 |
| Formula | C25H21F3N4O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2438125-72-3 |
| Synonyms | |
| SMILES | O=C1C=C(C(N1C2C(NC(CC2)=O)=O)=O)NC3=CC=CC(CCC(NC4=CC=CC(C(F)(F)F)=C4)=O)=C3 |
Biological Activity
| Description | ALV-05-077-01 is a selective degrader of BCL6 and BCL6B proteins. It effectively reduces endogenous BCL6 levels in SuDHL4 cells and BCL6B levels in KYO1 cells, both of which exhibit high expression of these proteins. This compound is useful for investigating the role of BCL6 and BCL6B in hematological malignancies and provides insight into potential therapeutic strategies targeting these proteins. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
