Product Data Sheet

CHF-2993

Catalog No. B19659

main product photo
CHF-2993 is an orally active anticonvulsant agent that functions primarily through the antagonism of GABA receptor modulators, specifically Bicuculline and Picrotoxin, to inhibit tonic convulsions in murine models. It shows no effect on Pentylenetetrazole-induced clonic convulsions but partially decreases Veratridine-induced aspartate efflux in rat cortical synaptosomes. CHF-2993 serves as a valuable tool in the investigation of epilepsy and related neurological disorders.
Chemical Information
Catalog NumB19659
M. Wt220.27
FormulaC12H16N2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.202914-21-4
Synonyms
SMILESN([C@H](C(N)=O)CO)C1CC=2C(C1)=CC=CC2
Biological Activity
DescriptionCHF-2993 is an orally active anticonvulsant agent that functions primarily through the antagonism of GABA receptor modulators, specifically Bicuculline and Picrotoxin, to inhibit tonic convulsions in murine models. It shows no effect on Pentylenetetrazole-induced clonic convulsions but partially decreases Veratridine-induced aspartate efflux in rat cortical synaptosomes. CHF-2993 serves as a valuable tool in the investigation of epilepsy and related neurological disorders.
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