Product Data Sheet

Elsunersen

Catalog No. B19704

main product photo
Elsunersen is an antisense oligonucleotide designed to selectively reduce the expression of the SCN2A gene, which encodes the voltage-gated sodium channel Nav1.2. This compound is instrumental in researching SCN2A developmental and epileptic encephalopathy (SCN2A-DEE), a neurological disorder characterized by severe seizures and developmental impairments. By targeting SCN2A, Elsunersen facilitates the exploration of therapeutic approaches for conditions arising from SCN2A mutations.
Chemical Information
Catalog NumB19704
M. Wt7044.71
FormulaC230H320N67O126P19S13
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2756001-75-7
SynonymsPRAX-222
SMILES[Elsunersen]
Biological Activity
DescriptionElsunersen is an antisense oligonucleotide designed to selectively reduce the expression of the SCN2A gene, which encodes the voltage-gated sodium channel Nav1.2. This compound is instrumental in researching SCN2A developmental and epileptic encephalopathy (SCN2A-DEE), a neurological disorder characterized by severe seizures and developmental impairments. By targeting SCN2A, Elsunersen facilitates the exploration of therapeutic approaches for conditions arising from SCN2A mutations.
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