Product Data Sheet
NLS-CPP
Catalog No. B19912
NLS-CPP is a nuclear localization signal (NLS)-cell-penetrating peptide derived from the NLS of OCT6, specifically designed to enhance nuclear delivery of biomolecules. This peptide is instrumental in facilitating the transport of therapeutic agents into the nucleus, thereby optimizing their biological efficacy. NLS-CPP has significant applications in research related to chronic inflammatory diseases, such as metabolic dysfunction-associated steatohepatitis (MASH) and osteoarthritis (OA). Its ability to promote nuclear uptake positions it as a valuable tool in drug delivery and cellular signaling studies.
Chemical Information
| Catalog Num | B19912 |
|---|---|
| M. Wt | 1558.74 |
| Formula | C63H115N25O21 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1228086-59-6 |
| Synonyms | NLS-cell penetrating peptide |
| SMILES | [C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@@H](C)O)C(O)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)(NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)N)=O)CCC(O)=O)=O)CCC(O)=O)=O)C)=O)C)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCNC(=N)N |
Biological Activity
| Description | NLS-CPP is a nuclear localization signal (NLS)-cell-penetrating peptide derived from the NLS of OCT6, specifically designed to enhance nuclear delivery of biomolecules. This peptide is instrumental in facilitating the transport of therapeutic agents into the nucleus, thereby optimizing their biological efficacy. NLS-CPP has significant applications in research related to chronic inflammatory diseases, such as metabolic dysfunction-associated steatohepatitis (MASH) and osteoarthritis (OA). Its ability to promote nuclear uptake positions it as a valuable tool in drug delivery and cellular signaling studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
