Product Data Sheet
Chlovalicin
Catalog No. B20644
Chlovalicin is an antifungal compound derived from the Sporothrix sp. FO-4649 strain, demonstrating significant anticancer properties. It effectively inhibits the proliferation of L6-dependent MH60 cells in the presence of IL-6, with an IC50 value of 7.5 μM, and also shows inhibitory effects on B16 melanoma cells at an IC50 of 38 μM. Additionally, Chlovalicin exhibits potential in modulating osteoclastogenesis, making it a valuable reagent for cancer research and studies on bone metabolism.
Chemical Information
| Catalog Num | B20644 |
|---|---|
| M. Wt | 332.82 |
| Formula | C16H25ClO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 179799-38-3 |
| Synonyms | |
| SMILES | O[C@@]1([C@@]2([C@H](O2)C/C=C(C)\C)C)[C@](O)(CCC([C@H]1OC)=O)CCl |
Biological Activity
| Description | Chlovalicin is an antifungal compound derived from the Sporothrix sp. FO-4649 strain, demonstrating significant anticancer properties. It effectively inhibits the proliferation of L6-dependent MH60 cells in the presence of IL-6, with an IC50 value of 7.5 μM, and also shows inhibitory effects on B16 melanoma cells at an IC50 of 38 μM. Additionally, Chlovalicin exhibits potential in modulating osteoclastogenesis, making it a valuable reagent for cancer research and studies on bone metabolism. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
