Product Data Sheet
Methyl betulonate
Catalog No. B21173
Methyl betulonate, a triterpenoid derivative of betulonic acid, exhibits potent inhibitory effects on cell growth across various tumor cell lines, including those resistant to conventional treatments. This compound demonstrates an IC50 greater than 50.0 μM in inhibiting the proliferation of eight tumor and two normal fibroblast cell lines. Methyl betulonate is valuable in cancer research, particularly for studies focused on understanding the mechanisms of tumor cell resistance and evaluating potential anti-cancer therapies.
Chemical Information
| Catalog Num | B21173 |
|---|---|
| M. Wt | 468.71 |
| Formula | C31H48O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 4356-31-4 |
| Synonyms | Betulonic acid methyl ester; Methyl 3-oxolup-20(29)-en-28-oate |
| SMILES | COC([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)(C(CC5)=O)C)([H])CC4)C)([H])CC3)C)C)=O |
Biological Activity
| Description | Methyl betulonate, a triterpenoid derivative of betulonic acid, exhibits potent inhibitory effects on cell growth across various tumor cell lines, including those resistant to conventional treatments. This compound demonstrates an IC50 greater than 50.0 μM in inhibiting the proliferation of eight tumor and two normal fibroblast cell lines. Methyl betulonate is valuable in cancer research, particularly for studies focused on understanding the mechanisms of tumor cell resistance and evaluating potential anti-cancer therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
