Product Data Sheet
Dibenz[a,h]anthracene
Catalog No. B21288
Dibenz[a,h]anthracene (DBA) acts as a potent agonist of the aryl hydrocarbon receptor (AhR) and is classified as a polycyclic aromatic hydrocarbon. It is known for its significant carcinogenic properties, inducing dose-dependent increases in DNA adduct formation and mutation frequency in lacZ assays. Additionally, DBA has been shown to upregulate the St3gal5 gene. This reagent is applicable in cancer research, particularly in studies examining mechanisms of carcinogenesis and the role of AhR signaling in tumor development.
Chemical Information
| Catalog Num | B21288 |
|---|---|
| M. Wt | 278.35 |
| Formula | C22H14 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 53-70-3 |
| Synonyms | DBA; 1,2,5,6-Dibenzanthracene; Benzo[k]tetraphene |
| SMILES | C12=CC=CC=C1C3=CC(C=CC4=CC=CC=C45)=C5C=C3C=C2 |
Biological Activity
| Description | Dibenz[a,h]anthracene (DBA) acts as a potent agonist of the aryl hydrocarbon receptor (AhR) and is classified as a polycyclic aromatic hydrocarbon. It is known for its significant carcinogenic properties, inducing dose-dependent increases in DNA adduct formation and mutation frequency in lacZ assays. Additionally, DBA has been shown to upregulate the St3gal5 gene. This reagent is applicable in cancer research, particularly in studies examining mechanisms of carcinogenesis and the role of AhR signaling in tumor development. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
