Product Data Sheet

N,N-dimethyldithiocarbamate potassium

Catalog No. B21296

main product photo
N,N-dimethyldithiocarbamate potassium is an inhibitor of the ubiquitin-activating enzyme E1, leading to a decrease in the levels of activated ubiquitinated E1 (ub-E1). This compound is known to elevate intracellular copper levels, enhance oxidative stress, raise protein carbonyl levels, and promote the expression of heme oxygenase-1 (HO-1). N,N-dimethyldithiocarbamate potassium is particularly relevant for research into neurodegenerative disorders, including Parkinson's disease, by elucidating the impact of ubiquitin pathways on cellular stress responses.
Chemical Information
Catalog NumB21296
M. Wt159.31
FormulaC3H6KNS2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.128-03-0
Synonyms
SMILESS=C(N(C)C)S[K]
Biological Activity
DescriptionN,N-dimethyldithiocarbamate potassium is an inhibitor of the ubiquitin-activating enzyme E1, leading to a decrease in the levels of activated ubiquitinated E1 (ub-E1). This compound is known to elevate intracellular copper levels, enhance oxidative stress, raise protein carbonyl levels, and promote the expression of heme oxygenase-1 (HO-1). N,N-dimethyldithiocarbamate potassium is particularly relevant for research into neurodegenerative disorders, including Parkinson's disease, by elucidating the impact of ubiquitin pathways on cellular stress responses.
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