Product Data Sheet
p,p'-DDE
Catalog No. B21382
p,p'-DDE (4,4'-DDE) serves as a potent androgen receptor antagonist, exhibiting an IC50 value of 5 μM and a Ki of 3.5 μM. This compound plays a significant role in the disruption of male reproductive system development and function. Furthermore, elevated levels of p,p'-DDE in serum have been associated with an increased risk of type 2 diabetes in women, highlighting its relevance in endocrine disruption studies and metabolic research.
Chemical Information
| Catalog Num | B21382 |
|---|---|
| M. Wt | 318.03 |
| Formula | C14H8Cl4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 72-55-9 |
| Synonyms | 4,4'-DDE; p,p'-Dichlorodiphenyldichloroethylene |
| SMILES | Cl/C(Cl)=C(C1=CC=C(Cl)C=C1)/C2=CC=C(Cl)C=C2 |
Biological Activity
| Description | p,p'-DDE (4,4'-DDE) serves as a potent androgen receptor antagonist, exhibiting an IC50 value of 5 μM and a Ki of 3.5 μM. This compound plays a significant role in the disruption of male reproductive system development and function. Furthermore, elevated levels of p,p'-DDE in serum have been associated with an increased risk of type 2 diabetes in women, highlighting its relevance in endocrine disruption studies and metabolic research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
