Product Data Sheet
Sudan IV
Catalog No. B21568
Sudan IV is a fat-soluble disazo dye that functions as an agonist of the aryl hydrocarbon receptor (AhR), activating downstream signaling pathways and inducing the expression of CYP1A1. This compound enhances CYP1A1 gene transcription through the formation of AhR-ARNT heterodimers and binding to xenobiotic response elements (XREs) in DNA, thereby increasing drug-metabolizing enzyme activity. Sudan IV is utilized in research to investigate the toxicity mechanisms associated with industrial dyes and to explore the effects of serum protein interactions, such as with bovine serum albumin (BSA), on in vivo distribution. Additionally, it serves as a stain for lipids, triglycerides, and lipoproteins in frozen tissue sections.
Chemical Information
| Catalog Num | B21568 |
|---|---|
| M. Wt | 380.44 |
| Formula | C24H20N4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 85-83-6 |
| Synonyms | Solvent Red 24; C.I. 26105 |
| SMILES | OC1=CC=C2C=CC=CC2=C1/N=N/C3=CC=C(/N=N/C4=CC=CC=C4C)C=C3C |
Biological Activity
| Description | Sudan IV is a fat-soluble disazo dye that functions as an agonist of the aryl hydrocarbon receptor (AhR), activating downstream signaling pathways and inducing the expression of CYP1A1. This compound enhances CYP1A1 gene transcription through the formation of AhR-ARNT heterodimers and binding to xenobiotic response elements (XREs) in DNA, thereby increasing drug-metabolizing enzyme activity. Sudan IV is utilized in research to investigate the toxicity mechanisms associated with industrial dyes and to explore the effects of serum protein interactions, such as with bovine serum albumin (BSA), on in vivo distribution. Additionally, it serves as a stain for lipids, triglycerides, and lipoproteins in frozen tissue sections. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
