Product Data Sheet

Physostigmine

Catalog No. B21803

main product photo
Physostigmine, a reversible acetylcholinesterase (AChE) inhibitor, effectively increases acetylcholine levels in the central nervous system by crossing the blood-brain barrier. This compound enhances cholinergic neurotransmission and has been shown to reverse memory deficits in transgenic mice models of Alzheimer's disease. Additionally, Physostigmine serves as a critical antidote for anticholinergic poisoning, providing valuable insights for neuropharmacological research and therapeutic applications.
Chemical Information
Catalog NumB21803
M. Wt275.35
FormulaC15H21N3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.57-47-6
SynonymsEserine
SMILESCN1[C@](N(C)CC2)([H])[C@]2(C)C3=C1C=CC(OC(NC)=O)=C3
Biological Activity
DescriptionPhysostigmine, a reversible acetylcholinesterase (AChE) inhibitor, effectively increases acetylcholine levels in the central nervous system by crossing the blood-brain barrier. This compound enhances cholinergic neurotransmission and has been shown to reverse memory deficits in transgenic mice models of Alzheimer's disease. Additionally, Physostigmine serves as a critical antidote for anticholinergic poisoning, providing valuable insights for neuropharmacological research and therapeutic applications.
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SHIPPING AND STORAGE
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