Product Data Sheet
IKVAVC
Catalog No. B21819
IKVAVC is a modified peptide of IKVAV, featuring a cysteine residue at the C-terminus that facilitates covalent conjugation to various molecular platforms. It functions as a neural adhesion and differentiation signaling peptide, preserving the biological activities of IKVAV. IKVAVC inhibits fibroblast migration and activation, downregulates the TGF-β1 signaling pathway and endoplasmic reticulum stress, and supports nerve repair. Additionally, it promotes a phenotypic shift in macrophages from the pro-inflammatory M1 state to the pro-reparative M2 state, thereby enhancing tissue regeneration processes.
Chemical Information
| Catalog Num | B21819 |
|---|---|
| M. Wt | 631.83 |
| Formula | C28H53N7O7S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1187540-64-2 |
| Synonyms | |
| SMILES |
Biological Activity
| Description | IKVAVC is a modified peptide of IKVAV, featuring a cysteine residue at the C-terminus that facilitates covalent conjugation to various molecular platforms. It functions as a neural adhesion and differentiation signaling peptide, preserving the biological activities of IKVAV. IKVAVC inhibits fibroblast migration and activation, downregulates the TGF-β1 signaling pathway and endoplasmic reticulum stress, and supports nerve repair. Additionally, it promotes a phenotypic shift in macrophages from the pro-inflammatory M1 state to the pro-reparative M2 state, thereby enhancing tissue regeneration processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
