Product Data Sheet

p5RHH

Catalog No. B21854

main product photo
p5RHH is an acid-activated membrane-lytic peptide derived from melittin, designed to facilitate siRNA delivery. This peptide promotes the synchronous disassembly of nanocomplexes and induces endosomal lysis in response to acidic pH levels, effectively triggering the release of siRNA into the cytoplasm through macropinocytosis. p5RHH is valuable for research applications focusing on gene silencing and RNA interference strategies.
Chemical Information
Catalog NumB21854
M. Wt2542.02
FormulaC112H189N41O25S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1423724-82-6
Synonyms
SMILES
Biological Activity
Descriptionp5RHH is an acid-activated membrane-lytic peptide derived from melittin, designed to facilitate siRNA delivery. This peptide promotes the synchronous disassembly of nanocomplexes and induces endosomal lysis in response to acidic pH levels, effectively triggering the release of siRNA into the cytoplasm through macropinocytosis. p5RHH is valuable for research applications focusing on gene silencing and RNA interference strategies.
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