Product Data Sheet

Methoxyfenoterol

Catalog No. B21954

main product photo
Methoxyfenoterol is a selective β2-adrenergic receptor agonist known for its ability to stimulate intracellular cAMP accumulation. It exhibits significant anti-proliferative effects on tumor cells by inducing G1 cell cycle arrest, upregulating p27, and downregulating cyclin D1 and cyclin A levels, while also inhibiting Akt phosphorylation. Additionally, Methoxyfenoterol is capable of crossing the blood-brain barrier, demonstrating efficacy in inhibiting the growth of astrocytoma xenografts. This compound is primarily utilized in research related to astrocytoma and glioblastoma.
Chemical Information
Catalog NumB21954
M. Wt317.38
FormulaC18H23NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.47308-67-8
Synonyms
SMILESOC1=CC(C(CNC(CC2=CC=C(C=C2)OC)C)O)=CC(O)=C1
Biological Activity
DescriptionMethoxyfenoterol is a selective β2-adrenergic receptor agonist known for its ability to stimulate intracellular cAMP accumulation. It exhibits significant anti-proliferative effects on tumor cells by inducing G1 cell cycle arrest, upregulating p27, and downregulating cyclin D1 and cyclin A levels, while also inhibiting Akt phosphorylation. Additionally, Methoxyfenoterol is capable of crossing the blood-brain barrier, demonstrating efficacy in inhibiting the growth of astrocytoma xenografts. This compound is primarily utilized in research related to astrocytoma and glioblastoma.
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