High Purity Kinase Inhibitors on Signaling Pathways Material Safety Data Sheet

Section 1 - Chemical Product and Company Identification

Product Name: AS 602801 (Bentamapimod)
Catalog Number: A11296
Adooq Bioscience
Adooq Bioscience
              4000 Barranca Parkway, Suite 250
              Irvine, CA 92604
For information, call: 866-930-6790 (Toll Free)

Section 2 - Composition, Information on Components

CAS Number: 848344-36-5
Molecular Formula: C25H23N5O2S
Molecular Weight: 547.6
Synonyms: AS-602801, AS602801

Section 3 - Hazards Identification

Toxic. Contains a pharmaceutically active ingredient. Handling should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

Section 4 - First Aid Measures

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin: Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac.
Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician: Effects may be delayed. Ethanol may inhibit methanol metabolism.

Section 5 - Fire Fighting Measures

Suitable extinguishing agents: Protective equipment: wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Unusual fire hazard:emits toxic fumes such as carbon monoxide, etc.

Section 6 - Accidental Release Measures

After Inhalation: cordon off area of spill; wear self-contained breathing apparatus, protective clothing and heavy rubber gloves
Measures for cleaning/collecting absorb solutions with finely- powdered liquid-binding material (diatomite, universal binders); decontaminate surfaces and equipment by scrubbing with alcohol; dispose of contaminated material according to Section 13

Section 7 - Handling and Storage

Handling: void inhalation and contact with skin, eyes and clothing; material may be an irritant
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Keep containers tightly closed.

Section 8 - Exposure Controls, Personal Protection

Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR ยง1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Section 9 - Stability and reactivity

Stability: stable if stored as directed; avoid strong oxidizing agents
Thermal decomposition / conditions to be avoided: protect from light and heat
Dangerous products of decomposition: thermal ecomposition may produce toxic gases such as carbon monoxide, carbon dioxide, and nitrogen oxides

Section 10 - Toxicological information

Acute toxicity: not known
Primary irritant effect: not known
On the skin: not known
On the eye: not known

Section 11 - Ecological information

General notes: no data available

Section 12 - Disposal consideration

Dispose of in accordance with prevailing country, federal, state and local regulations

Section 13 - Transport information

Proper shipping name: none
Non-Hazardous for transport:
this substance is considered to be non-hazardous for transport

IATA class:
IATA class: none
Non-Hazardous for transport:
this substance is considered to be non-hazardous for transport

Section 14 - Regulations

Code letter and hazard designation of product:
Hazard-determining components of labeling:
EU Risk And Safety phrases:

S24/25: avoid contact with skin and eyes
S26: in case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S28: after contact with skin, wash immediately with plenty of water
S36/37/39: wear protective clothing, gloves and eye/face protection
R28: very toxic if swallowed
R38: irritating to skin
R41: risk of serious damages to eyes
R48: toxic; danger of serious damage to health by prolonged exposure
R62: possible risk of impaired fertility
R63: possible risk of harm to unborn child

Section 15 - Additional Information

MSDS Creation Date: 6/22/2012
Revision #2 Date: 1/14/2014
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Adooq bioscience be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Adooq bioscience has been advised of the possibility of such damages.