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AS 602801 (Bentamapimod)

Catalog No.: A11296

JNK inhibitor

AS 602801 (Bentamapimod)

AS 602801 (Bentamapimod) Chemical Structure

CAS NO. 848344-36-5

AS 602801 is a novel, orally active, Jun Kinase Inhibitor.

Availability: In stock

Package Price Qty
5 mg
$65.00
10 mg
$110.00
50 mg
$225.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Shuai Zhang, .et al. AS602801 sensitizes glioma cells to temozolomide and vincristine by blocking gap junction communication between glioma cells and astrocytes, J Cell Mol Med, 2021, Apr;25(8):4062-4072 PMID: 33609076
  • Kuramoto K, .et al. AS602801, an Anti-Cancer Stem Cell Drug Candidate, Suppresses Gap-junction Communication Between Lung Cancer Stem Cells and Astrocytes, Anticancer Res, 2018, Sep;38(9):5093-5099 PMID: 30194154

Biological Activity

AS 602801 is a novel, orally active, Jun Kinase Inhibitor.
In vitro DMSO 21 mg/mL (45.89 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.86 mL 109.29 mL 218.58 mL
0.5 mM 4.37 mL 21.86 mL 43.72 mL
1 mM 2.19 mL 10.93 mL 21.86 mL
5 mM 0.44 mL 2.19 mL 4.37 mL

*The above data is based on the productmolecular weight 457.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11296
Actions Inhibitor
CAS No. 848344-36-5
Formula C25H23N5O2S
M. Wt 457.5
Purity >98%
Synonyms AS-602801, AS602801
SMILES C1COCCN1CC2=CC=C(C=C2)COC3=NC=CC(=N3)C(C#N)C4=NC5=CC=CC=C5S4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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