AVL-292

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Btk inhibitor

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Catalog No. A13202

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AVL-292 5mg A13202-5

Regular Price: $60.00

Special Price: $51.00

AVL-292 10mg A13202-10

Regular Price: $90.00

Special Price: $76.50

AVL-292 25mg A13202-25

Regular Price: $170.00

Special Price: $144.50

AVL-292 50mg A13202-50

Regular Price: $260.00

Special Price: $221.00

AVL-292 10mM * 1mL in DMSO A13202-10mM-D

Regular Price: $65.00

Special Price: $55.25

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AVL-292 is a highly selective, covalent Btk inhibitor.

AVL-292

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Chemical Information

Catalog Num A13202
Actions Inhibitor
M. Wt 423.44
Formula C22H22FN5O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1202757-89-8
Synonyms AVL292, AVL 292, CC292, CC-292, CC 292
SMILES code COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F
Chemical Name N-(3-((5-fluoro-2-((4-(2-methoxyethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide

Biological Activity

Description
AVL-292 is a highly selective, covalent Btk inhibitor.
Targets
Target Value
BTKIC50: <0.5nM
YESIC50: 723nM
c-SrcIC50: 1.729μM
BRKIC50: 2.43μM
LynIC50: 4.401μM
FynIC50: 7.146μM
LCKIC50: 9.079μM
CSKIC50: >10μM
HckIC50: 14.46μM

Solubility

Solubility (25°C)* In vitro DMSO 85 mg/mL (200.73 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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