AZ 23

TrkA inhibitor

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Catalog No. A12666

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AZ 23 5mg A12666-5
$180.00
AZ 23 10mg A12666-10
$300.00
AZ 23 25mg A12666-25
$600.00
AZ 23 50mg A12666-50
$1,000.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AZ 23 is a potent and selective tyrosine kinase Trk inhibitor with IC50 to 2 and 8 nM for TrkA and TrkB respectively

AZ 23

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Chemical Information

Catalog Num A12666
Actions Inhibitor
M. Wt 391.83
Formula C17H19ClFN7O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 915720-21-7
Synonyms AZ23, AZ-23
SMILES code C[[email protected]@H](C1=NC=C(C=C1)F)NC2=NC=C(C(=N2)NC3=CC(=NN3)OC(C)C)Cl
Chemical Name 5-Chloro-N-[(1S)-1-(5-fluoropyridin-2-yl)ethyl]-N'-(5-isopropoxy-1H-pyrazol-3-yl)pyrimidine-2,4-diamine

Biological Activity

Description
AZ 23 is a potent and selective tyrosine kinase Trk inhibitor with IC50 to 2 and 8 nM for TrkA and TrkB respectively

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