Cytochrome P450



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Catalog No. Product Name Application Product Information
A13365

3-Cyano-7-ethoxycoumarin

Fluorescent P450 substrate
3-Cyano-7-ethoxycoumarin is a fluorogenic substrate suitable for the continuous determination of cytochrome P450 mixed-function monooxygenases. It is a fluorescent probe useful in microsomal dealkylase studies.
A10020 SALE

Abiraterone (CB-7598)

CYP17 inhibitor
Abiraterone (CB-7598) inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1), an enzyme which is expressed in testicular, adrenal, and prostatic tumor tissues.
A11058 SALE

Abiraterone Acetate (CB7630)

CYP17 inhibitor
Abiraterone acetate (CB7630) is an orally active acetate ester of the steroidal compound Abiraterone with antiandrogen activity. Abiraterone inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1).
A13361 SALE

ABT

Cytochrome P450 inhibitor
ABT (1-Aminobenzotriazole )is a suicide substrate for (CYP)cytochrome P-450 and chloroperoxidase.
A10081 SALE

Apigenin

Protein kinase inhibitor

Apigenin, found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally-occurring glycosides. Apigenin acts as a monoamine transporter activator, one of the few chemicals demonstrated to possess this property. Apigenin is a ligand for central benzodiazepine receptors that competitively inhibited the binding of flunitrazepam with a Ki of 4μM, exerting anxiolytic and slight sedative effects.

A10102 SALE

Avasimibe (CI-1011)

CYP17 inhibitor
Avasimibe (CI-1011) is an orally bioavailable Acyl-CoA:Cholesterol O-Acyltransferase (ACAT) inhibitor.
A10120

Baicalein

Lipoxygenase Inhibitor

Baicalein is a flavonoid originally isolated from the roots of Scutellaria baicalensis Georgi. Baicalein inhibits lipid peroxidation, as assessed by production of TBARS, with an IC50 value of 5 µM.

A10200 SALE

Chloramphenicol

-
Chloramphenicol is a bacteriostatic antimicrobial.
A10225 SALE

Clarithromycin

cytochrome P4503A4 inhibitor
Clarithromycin is a macrolide antibiotic. It prevents bacteria from growing by interfering with their protein synthesis.
A10234 SALE

Clotrimazole

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Action of clotrimazole is against the division and growing of fungi.Clotrimazole alters the permeability of the fungal cell wall and inhibits the activity of enzymes within the cell. It specifically inhibits the biosynthesis of ergosterol and other sterols required for cell membrane production.
A11277 SALE

Cobicistat (GS-9350)

CYP3A Inhibitor
Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir and tenofovir alafenamide fumarate.
A10267

Cytochrome P450 14a-demethylase inhibitor 1a

-
A10268

Cytochrome P450 14a-demethylase inhibitor 1b

-
A10269

Cytochrome P450 14a-demethylase inhibitor 1c

-
A10270

Cytochrome P450 14a-demethylase inhibitor 1d

-
A10271

Cytochrome P450 14a-demethylase inhibitor 1e

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A10272

Cytochrome P450 14a-demethylase inhibitor 1f

-
A10273

Cytochrome P450 14a-demethylase inhibitor 1g

-
A10274

Cytochrome P450 14a-demethylase inhibitor 1h

-
A10275

Cytochrome P450 14a-demethylase inhibitor 1i

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A10276

Cytochrome P450 14a-demethylase inhibitor 1j

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A10277

Cytochrome P450 14a-demethylase inhibitor 1k

-
A10278

Cytochrome P450 14a-demethylase inhibitor 1L

-
A10279

Cytochrome P450 14a-demethylase inhibitor 1m

-
A10280

Cytochrome P450 14a-demethylase inhibitor 1n

-

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