Debio-1347 (CH5183284)

FGFR1/2/3 inhibitor

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Catalog No. A14415

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Debio-1347 5mg A14415-5
$110.00
Debio-1347 10mg A14415-10
$190.00
Debio-1347 25mg A14415-25
$330.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Debio-1347 is an orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential antineoplastic activity.

Debio-1347 (CH5183284)

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Chemical Information

Catalog Num A14415
Actions Inhibitor
M. Wt 356.38
Formula C20H16N6O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1265229-25-1
Synonyms Debio 1347, Debio1347, CH5183284, CH 5183284, CH-5183284, FF-284, FF284, FF 284
SMILES code CC1=NC2=C(N1)C=C(C=C2)N3C(=C(C=N3)C(=O)C4=CC5=CC=CC=C5N4)N
Chemical Name (5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone

Biological Activity

Description
Debio-1347 is an orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential antineoplastic activity.
Targets
FGFR2 FGFR1 FGFR3 FGFR4
7.6 nM9.3 nM22 nM290 nM

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