E7080 (Lenvatinib)

E7080 is a multi-kinase inhibitor that inhibits both VEGFR2 and VEGFR3 kinases.
Grouped product items
Product Name Price Stock Qty
E7080 5mg
$50.00
In stock
E7080 10mg
$70.00
In stock
E7080 50mg
$150.00
In stock
E7080 100mg
$200.00
In stock
E7080 (Lenvatinib) 10mM * 1mL in DMSO
$50.00
In stock
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Adooq Products cited in reputable paper
Adooq's E7080 (Lenvatinib) has been cited by 8 publications
  • Mai Nakahara, .et al. , Biomed Rep, 2022, Aug 3;17(4):78 PMID: 36158319
  • Paula Sagmeister, .et al. , J Hepatocell Carcinoma, 2022, Jul 9;9:595-607 PMID: 35845819
  • Aya Hasan Alshammari, .et al. , Biochem Pharmacol, 2022, Mar;197:114914 PMID: 35041812
  • Keisuke Enomoto, .et al. , Cancers (Basel), 2021, Feb 18;13(4):862 PMID: 33670725
  • Jindal A, .et al. , J Transl Sci, 2020, 7: 1-10
  • Koide H, .et al. , Xenobiotica, 2018, Oct;48(10):1059-1071 PMID: 29034773
  • Fujita KI, .et al. , J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358
  • Tomoko Ogawa-Morita, .et al. , Int J Anal Chem, 2017, 2017: 2341876 PMID: 28680445
  • Biological Activity
    Discription E7080 is a multi-kinase inhibitor that inhibits both VEGFR2 and VEGFR3 kinases.
    Targets
    Target Value
    Product Information
    Catalog Num A10340
    Formula C21H19ClN4O4
    Molecular Weight 426.9
    CAS Number 417716-92-8
    SMILES COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 35 mg/mL (81.99 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% methylcellulose 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.42 mL 117.12 mL 234.25 mL
    0.5 mM 4.68 mL 23.42 mL 46.85 mL
    1 mM 2.34 mL 11.71 mL 23.42 mL
    5 mM 0.47 mL 2.34 mL 4.68 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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