GW2580
GW2580 is a small-molecule, ATP-competitive inhibitor of cFMS kinase.
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Adooq's GW2580 has been cited by 2 publications
- Ravikanth Maddipati, .et al. , bioRxiv, 2021, February 01
- Liu M, .et al. , Nat Immunol, 2019, Jan 21 PMID: 30664738
Biological Activity
| Description | GW2580 is a small-molecule, ATP-competitive inhibitor of cFMS kinase. | |||||
|---|---|---|---|---|---|---|
| Cell Research |
|
Product Information
| Catalog Num | A11959 |
|---|---|
| Formula | C20H22N4O3 |
| Molecular Weight | 366.41 |
| CAS Number | 870483-87-7 |
| SMILES | COC1=CC=C(C=C1)COC2=C(C=C(C=C2)CC3=CN=C(N=C3N)N)OC |
| Synonyms | GW 2580, GW-2580 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 48 mg/mL (131 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.29 mL | 136.46 mL | 272.92 mL |
| 0.5 mM | 5.46 mL | 27.29 mL | 54.58 mL |
| 1 mM | 2.73 mL | 13.65 mL | 27.29 mL |
| 5 mM | 0.55 mL | 2.73 mL | 5.46 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
