United States
You have no items in your shopping cart.
Publications citing Adooq Products
Chemical Information
| Catalog Num | A11924 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 352.3 |
| Formula | C19H16N2O5 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 931398-72-0 |
| Synonyms | IOX-2, IOX2 |
| SMILES code | C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=C(C2=O)C(=O)NCC(=O)O)O |
| Chemical Name | N-[[1,2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]glycine |
Description |
IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM in a cell-free assay, >100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH. | ||||||||||
Targets |
|
||||||||||
| Solubility (25°C)* | In vitro | DMSO | 7 mg/mL (19.86 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
Ordering online
To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.
To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.
When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards. We will then liaise with you or your purchasing department to confirm the order.
Found your products but not ready to order?
Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.
Ordering offline
You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order. Our contact details are:
- Tel: 866-930-6790
- Fax: 323-606-8156
- Email: [email protected]
We require the following information to process your order:
- The catalog number for each product.
- Your email address or fax number.
- Your name and telephone number.
- Shipping address and billing address.
- Purchase order numbers.
Similar product(s)
Special Price Starting at:
$63.00
KC7F2 is an inhibitor of HIF-1?? protein translation, but not transcription, that suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E bin ...
Special Price Starting at: $63.00
Special Price Starting at:
$63.00
BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I. ...
Special Price Starting at: $63.00
Special Price Starting at:
$120.00
FM19G11 is an inhibitor of Hypoxia Inducible Factors α (HIFα), which are transcription factors that respond to changes in available oxygen in the cellular environment.
...
Special Price Starting at: $120.00
Special Price Starting at:
$36.00
2-Methoxyestradiol is an apoptotic, antiproliferative and antiangiogenic agent. Induces p53-induced apoptosis via two pathways: activation of p38 and NF-κB; and activation of JNK and AP-1 leading to ...
Special Price Starting at: $36.00
Special Price Starting at:
$170.00
ML-228 is an activator of the HIF signaling pathway, as demonstrated by HIF response element (HRE) reporter assay, HIF-1?? nuclear translocation assay, and increased VEGF expression. ...
Special Price Starting at: $170.00
Special Price Starting at:
$150.00
Chetomin is reported to be an antibiotic metabolite of Chaetomium spp. which contains bacteriostatic effects on Gram-positive bacteria. ...
Special Price Starting at: $150.00
Special Price Starting at:
$220.00
HIF-C2 is a potent and selective allosteric inhibitor of hypoxia inducible factor-2 (HIF-2) ...
Special Price Starting at: $220.00
Special Price Starting at:
$54.00
FG-4592 is a novel hypoxia inducible factor prolyl hydroxylase inhibitor, in CKD anemia. ...
Special Price Starting at: $54.00
Keywords:buy IOX 2 | IOX 2 Supplier | purchase IOX 2 | IOX 2 cost | IOX 2 manufacturer | order IOX 2 | IOX 2 distributor | buy 931398-72-0| 931398-72-0 Supplier | purchase 931398-72-0 | 931398-72-0 cost | 931398-72-0 manufacturer | order 931398-72-0 | 931398-72-0 distributor