JI-101

VEGFR2/PDGFRβ/EphB4 inhibitor

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Catalog No. A13545

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
JI-101 5mg A13545-5
$350.00
JI-101 10mg A13545-10
$600.00
JI-101 25mg A13545-25
$1,200.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor beta (PDGFRβ), and the ephrin B4 receptor B4 (EphB4) with potential antiangiogenic and antineoplastic activities.

JI-101

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Chemical Information

Catalog Num A13545
Actions Inhibitor
M. Wt 466.3305
Formula C22H20BrN5O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 900573-88-8
Synonyms JI 101, JI101
SMILES code COC1=C(C=C(C=C1)Br)NC(=O)NC2=CC=CC3=C2C=CN3CC4=CC(=NC=C4)N
Chemical Name 1-(1-((2-aminopyridin-4-yl)methyl)-1H-indol-4-yl)-3-(5-bromo-2-methoxyphenyl)urea.

Biological Activity

Description
JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor beta (PDGFRβ), and the ephrin B4 receptor B4 (EphB4) with potential antiangiogenic and antineoplastic activities.

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