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KRCA-0008

ACK1/ALK inhibitor

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Catalog No. A15511

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
KRCA-0008 10mg A15511-10

Regular Price: $110.00

Special Price: $88.00

KRCA-0008 25mg A15511-25

Regular Price: $200.00

Special Price: $160.00

KRCA-0008 50mg A15511-50

Regular Price: $390.00

Special Price: $312.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

KRCA-0008 is a potent and selective ALK/Ack1 inhibitor with IC50 of 12 nM/4 nM for ALK and Ack1 respectively; displays drug-like properties without hERG liability.

KRCA-0008

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Chemical Information

Catalog Num A15511
Actions Inhibitor
M. Wt 609.12
Formula C30H37ClN8O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1472795-20-2
Synonyms KRCA 0008, KRCA0008
SMILES code CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC(=NC=C3Cl)NC4=C(C=C(C=C4)N5CCN(CC5)C(=O)C)OC)OC
Chemical Name 1-[4-[4-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxyanilino]-5-chloropyrimidin-4-yl]amino]-3-methoxyphenyl]piperazin-1-yl]ethanone

Biological Activity

Description
KRCA-0008 is a potent and selective ALK/Ack1 inhibitor with IC50 of 12 nM/4 nM for ALK and Ack1 respectively; displays drug-like properties without hERG liability.

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