MI-773
Catalog No.: A15440
MDM2 inhibitor
MI-773 is an orally available MDM2 antagonist with Ki of 0.88 nM.
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Biological Activity
| Description | MI-773 is an orally available MDM2 antagonist with Ki of 0.88 nM. | ||
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| Targets |
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Product Information
| Catalog Num | A15440 |
|---|---|
| Formula | C29H34Cl2FN3O3 |
| Molecular Weight | 562.5 |
| CAS Number | 1303607-60-4 |
| SMILES | CC(C)(C)C[C@H]1[C@@]2([C@H]([C@@H](N1)C(=O)NC3CCC(CC3)O)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(C=C5)Cl)NC2=O |
| Synonyms | SAR405838,MI 773, MI773 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 93 mg/mL (165.33 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 29 mg/mL (51.55 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.78 mL | 88.89 mL | 177.78 mL |
| 0.5 mM | 3.56 mL | 17.78 mL | 35.56 mL |
| 1 mM | 1.78 mL | 8.89 mL | 17.78 mL |
| 5 mM | 0.36 mL | 1.78 mL | 3.56 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
