PF-543 Citrate

Name: PF-543 Citrate
Brand: Adooq Bioscience
SKU: A15210
Rating: 5 (288 reviews)

Catalog No.: A15210

SphK1 Inhibitor

PF-543 Citrate is a novel cell-permeant inhibitor of SphK1 with a K(i) of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.

Skip to the end of the images gallery

PF-543 Citrate 1415562-83-2 SphK1 Inhibitor

Skip to the beginning of the images gallery

Grouped product items
Size	Price	Stock
2mg	$35.00	In stock
5mg	$70.00	In stock
10mg	$120.00	In stock
50mg	$370.00	In stock
100mg	$570.00	In stock
Bulk Size	Bulk Discount

Bulk Inquiry

Notify me when the price drops

Free Delivery on orders over $500

Research use only. We do not sell to patients.

Data Sheet SDS

Loading distributor info...

Adooq Products cited in reputable paper

Biological Activity

Description	PF-543 Citrate is a novel cell-permeant inhibitor of SphK1 with a K(i) of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.

Product Information

Catalog Num	A15210
Formula	C33H39NO11S
Molecular Weight	657.73
CAS Number	1415562-83-2
SMILES	CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCCC3CO)CS(=O)(=O)C4=CC=CC=C4.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
Synonyms	PF543 Citrate, PF 543 Citrate
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	85 mg/mL (169.3 mM)
	Water	Insoluble
	Ethanol	85 mg/mL (169.3 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.2 mL	76.02 mL	152.04 mL
0.5 mM	3.04 mL	15.2 mL	30.41 mL
1 mM	1.52 mL	7.6 mL	15.2 mL
5 mM	0.3 mL	1.52 mL	3.04 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂