Piceatannol

Syk Inhibitor

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Catalog No. A12162

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Piceatannol 10mg A12162-10
$66.00
Piceatannol 25mg A12162-25
$130.00
Piceatannol 50mg A12162-50
$190.00
Piceatannol 100mg A12162-100
$270.00
Piceatannol 10mM * 1mL in DMSO A12162-10mM-D
$73.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Piceatannol is an anti-inflammatory, immunomodulatory and antiproliferative agent. Inhibits p56lck and syk protein tyrosine kinases and inhibits TNF-induced NF-??B activation and gene expression.

Piceatannol

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Chemical Information

Catalog Num A12162
Actions Inhibitor
M. Wt 244.3
Formula C14H12O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 10083-24-6
Synonyms N/A
SMILES code C1=CC(=C(C=C1/C=C/C2=CC(=CC(=C2)O)O)O)O
Chemical Name 4-[(1E)-2-(3,5-Dihydroxyphenyl)ethe?nyl]-1,2-benzenediol

Biological Activity

Description
Piceatannol is an anti-inflammatory, immunomodulatory and antiproliferative agent. Inhibits p56lck and syk protein tyrosine kinases and inhibits TNF-induced NF-??B activation and gene expression.
Targets
Target Value
Syk
Lyn
PKAIC50: 3μM
PKCIC50: 8μM
MLCKIC50: 12μM
CDPKIC50: 19μM

Solubility

Solubility (25°C) * In vitro DMSO 48 mg/mL (196.52 mM)
Water <1 mg/mL (<1 mM)
Ethanol 48 mg/mL (196.52 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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