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PND-1186

FAK inhibitor

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Catalog No. A13140

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PND-1186 5mg A13140-5
$110.00
PND-1186 10mg A13140-10
$150.00
PND-1186 25mg A13140-25
$340.00
PND-1186 10mM * 1mL in DMSO A13140-10mM-D
$121.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PND-1186 is a potent FAK inhibitor with IC50 of 1.5 nM.

PND-1186

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Chemical Information

Catalog Num A13140
Actions Inhibitor
M. Wt 501.5
Formula C25H26F3N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1061353-68-1
Synonyms SR-2516, PND 1186, PND1186, SR 2516, SR2516
SMILES code CNC(=O)C1=CC=CC=C1NC2=CC(=NC=C2C(F)(F)F)NC3=C(C=C(C=C3)N4CCOCC4)OC
Chemical Name 2-((2-((2-methoxy-4-morpholinophenyl)amino)-5-(trifluoromethyl)pyridin-4-yl)amino)-N-methylbenzamide

Biological Activity

Description
PND-1186 is a potent FAK inhibitor with IC50 of 1.5 nM.
Targets
FAK
0.5 nM

Solubility

Solubility (25°C)* In vitro DMSO 24 mg/mL (47.85 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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