PP2

Catalog No.: A12723
Src Inhibitor
PP2 is a selective inhibitor of Src-family tyrosine kinases. Inhibits p56lck and p59fynT (IC50 values are 4 and 5 nM respectively). Displays > 10000-fold selectivity over ZAP-70 and JAK2. Moderately inhibits CSK (IC50 = 0.73 μM).
Grouped product items
Product Name Price Stock Qty
PP2 10mg
$100.00
In stock
PP2 25mg
$220.00
In stock
PP2 50mg
$300.00
In stock
PP2 100mg
$500.00
In stock
PP2 10mM * 1mL in DMSO
$90.00
In stock
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Biological Activity
Discription PP2 is a selective inhibitor of Src-family tyrosine kinases. Inhibits p56lck and p59fynT (IC50 values are 4 and 5 nM respectively). Displays > 10000-fold selectivity over ZAP-70 and JAK2. Moderately inhibits CSK (IC50 = 0.73 μM).
Targets
Target Value
Product Information
Catalog Num A12723
Formula C15H16ClN5
Molecular Weight 301.78
CAS Number 172889-27-9
SMILES CC(C)(C)N1C2=C(C(=N1)C3=CC=C(C=C3)Cl)C(=NC=N2)N
Synonyms PP-2, PP 2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 52 mg/mL (172.31 mM)
Water Insoluble
Ethanol 2 mg/mL (6.62 mM)
In vivo 4% DMSO+corn oil 2.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.14 mL 165.68 mL 331.37 mL
0.5 mM 6.63 mL 33.14 mL 66.27 mL
1 mM 3.31 mL 16.57 mL 33.14 mL
5 mM 0.66 mL 3.31 mL 6.63 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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