PRT-060318 is a novel selective inhibitor of the tyrosine kinase Syk, as an approach to HIT treatment.
Product Information
Catalog Num
A15524
Formula
C18H24N6O
Molecular Weight
340.42
CAS Number
1194961-19-7
SMILES
CC1=CC(=CC=C1)NC2=NC(=NC=C2C(=O)N)NC3CCCCC3N
Synonyms
PRT 060318, PRT060318, PRT318, P142?C76.
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
66 mg/mL (159.67 mM)
Water
66 mg/mL (159.67 mM)
Ethanol
Insoluble
In vivo
water
71 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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