RG7112

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selective p53-MDM2 inhibitor

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Catalog No. A11523

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
RG7112 5mg A11523-5

Regular Price: $180.00

Special Price: $144.00

RG7112 10mg A11523-10

Regular Price: $320.00

Special Price: $256.00

RG7112 50mg A11523-50

Regular Price: $960.00

Special Price: $768.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

RG7112 is the first clinical small-molecule MDM2 inhibitor designed to occupy the p53-binding pocket of MDM2.

RG7112

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Chemical Information

Catalog Num A11523
Actions Inhibitor
M. Wt 727.78
Formula C38H48Cl2N4O4S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 939981-39-2
Synonyms RG-7112, RG 7112, RO5045337
SMILES code No
Chemical Name [(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethylimidazol-1-yl]-[4-(3-methylsulfonylpropyl)piperazin-1-yl]methanone

Biological Activity

Description
RG7112 is the first clinical small-molecule MDM2 inhibitor designed to occupy the p53-binding pocket of MDM2.

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