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- H Yamaguchi ,etc. Saracatinib impairs the peritoneal dissemination of diffuse‐type gastric carcinoma cells resistant to Met and fibroblast growth factor receptor inhibitors. Cancer science, 2014, 105(5), 528-536.
- K Maruyama ,etc. 5-azacytidine-induced protein 2 (AZI2) regulates bone mass by fine-tuning osteoclast survival. Journal of Biological Chemistry, 2015, 290(15), 9377-9386.
- AL Jackson ,etc. Emerging therapies: angiogenesis inhibitors for ovarian cancer. Expert opinion on emerging drugs, 2015, 20(2), 331-346.
|Storage||at -20°C 2 years|
|Saracatinib (AZD0530) is a highly selective, orally available, dual-specific Src/Abl kinase inhibitor with IC50 of 2.7 and 30 nM for c-Src and Abl kinase, respectively.|
|Solubility (25°C) *||In vitro||DMSO||100 mg/mL (184.49 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||100 mg/mL (184.49 mM)|
|In vivo||0.5% methylcellulose/0.2% Tween 80||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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