Saracatinib (AZD0530)

Saracatinib (AZD0530) is a highly selective, orally available, dual-specific Src/Abl kinase inhibitor with IC50 of 2.7 and 30 nM for c-Src and Abl kinase, respectively.
Grouped product items
Product Name Price Stock Qty
Saracatinib 10mg
$60.00
In stock
Saracatinib 25mg
$90.00
In stock
Saracatinib 100mg
$220.00
In stock
Saracatinib 200mg
$390.00
In stock
Saracatinib (AZD0530) 10mM * 1mL in DMSO
$92.00
In stock
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Adooq Products cited in reputable paper
Adooq's Saracatinib (AZD0530) has been cited by 4 publications
  • Andromachi Lambrianidou, .et al. , Cell Signal, 2021, Apr;80:109912 PMID: 33388443
  • Chisato Naito, .et al. , Atherosclerosis, 2016, Mar;246:344-51 PMID: 26828753
  • Kenta Maruyama, .et al. , J Biol Chem, 2015, Apr 10; 290(15): 9377-9386 PMID: 25691576
  • Amanda L Jackson, .et al. , Expert Opin Emerg Drugs, 2015, Jun;20(2):331-46 PMID: 26001052
  • Biological Activity
    Discription Saracatinib (AZD0530) is a highly selective, orally available, dual-specific Src/Abl kinase inhibitor with IC50 of 2.7 and 30 nM for c-Src and Abl kinase, respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A10108
    Formula C27H32ClN5O5
    Molecular Weight 542
    CAS Number 379231-04-6
    SMILES CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 34 mg/mL (62.73 mM)
    Water Insoluble
    Ethanol 30 mg/mL (55.35 mM)
    In vivo 2% DMSO+30% PEG 300+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.45 mL 92.25 mL 184.5 mL
    0.5 mM 3.69 mL 18.45 mL 36.9 mL
    1 mM 1.85 mL 9.23 mL 18.45 mL
    5 mM 0.37 mL 1.85 mL 3.69 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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