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c-Met inhibitor

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Catalog No. A10869

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SU11274 5mg A10869-5

Regular Price: $60.00

Special Price: $48.00

SU11274 10mg A10869-10

Regular Price: $110.00

Special Price: $88.00

SU11274 50mg A10869-50

Regular Price: $480.00

Special Price: $384.00

SU11274 100mg A10869-100

Regular Price: $700.00

Special Price: $560.00

SU11274 10mM * 1mL in DMSO A10869-10mM-D

Regular Price: $127.00

Special Price: $101.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SU11274 is a Met tyrosine kinase inhibitor.


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Chemical Information

Catalog Num A10869
Actions Inhibitor
M. Wt 568.1
Formula C28H30CIN5O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 658084-23-2
Synonyms SU-11274, PKI-SU11274
SMILES code CC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)/C=C\3/C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O
Chemical Name (3Z)-N-(3-Chlorophenyl)-3-[[3,5-dimethyl-4-[(4-methyl-1-piperazinyl)carbonyl]-1H-pyrrol-2-yl]methylene]-2,3-dihydro-N-methyl-2-oxo-1H-indole-5-sulfonamide

Biological Activity

SU11274 is a Met tyrosine kinase inhibitor.
Target Value
MetIC50: 0.01μM
Flk1IC50: 1.25μM
RONIC50: 4.0μM
FGFR1IC50: 8.5μM
CDK2IC50: >10μM
PDGFRβIC50: >20μM
EGFRIC50: >100μM


Solubility (25°C) * In vitro DMSO 92 mg/mL (161.94 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (3.52 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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