TAPI-0 is a potent inhibitor of TACE (TNF-α converting enzyme, ADAM17) with an IC50 of 100 nM, effectively modulating TNF-α processing. This compound also exhibits inhibitory activity against matrix metalloproteinases (MMPs), making it valuable for studying inflammatory processes and the role of TNF-α in various disease states. TAPI-0 is relevant for research applications involving cancer, autoimmune diseases, and tissue remodeling.
TAPI-0 is a potent inhibitor of TACE (TNF-α converting enzyme, ADAM17) with an IC50 of 100 nM, effectively modulating TNF-α processing. This compound also exhibits inhibitory activity against matrix metalloproteinases (MMPs), making it valuable for studying inflammatory processes and the role of TNF-α in various disease states. TAPI-0 is relevant for research applications involving cancer, autoimmune diseases, and tissue remodeling.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
