TAPI-1

Catalog No.: A76778
TACE/ADAM17/MMP Inhibitor
TAPI-1 is a specific inhibitor of TACE (ADAM17) and also exhibits inhibitory activity against metalloproteinases (MMPs). By blocking the shedding of various cell surface proteins, TAPI-1 plays a critical role in modulating cellular signaling and processes. It is widely utilized in research applications related to inflammation, cancer, and tissue remodeling, providing valuable insights into the roles of proteolytic enzymes in disease mechanisms.
Grouped product items
Size Price Stock Qty
1mg
$155.00
In stock
5mg
$715.00
In stock
10mg
$1,310.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTAPI-1 is a specific inhibitor of TACE (ADAM17) and also exhibits inhibitory activity against metalloproteinases (MMPs). By blocking the shedding of various cell surface proteins, TAPI-1 plays a critical role in modulating cellular signaling and processes. It is widely utilized in research applications related to inflammation, cancer, and tissue remodeling, providing valuable insights into the roles of proteolytic enzymes in disease mechanisms.
Product Information
Catalog NumA76778
FormulaC26H37N5O5
Molecular Weight499.60
CAS Number163847-77-6
SMILESO=C(N[C@@H](CC1=CC=C2C=CC=CC2=C1)C(N[C@@H](C)C(NCCN)=O)=O)[C@H](CC(C)C)CC(NO)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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