Telatinib (BAY 57-9352) VEGFR-2 inhibitor

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Catalog No. A10903

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Telatinib 5mg A10903-5
$90.00
Telatinib 10mg A10903-10
$160.00
Telatinib 50mg A10903-50
$450.00
Telatinib 100mg A10903-100
$750.00
Telatinib (BAY 57-9352) 10mM * 1mL in DMSO A10903-10mM-D
$133.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Telatinib (BAY 57-9352) is an orally available, small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3) and platelet-derived growth factor receptor β tyrosine kinases.

Telatinib (BAY 57-9352)

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Chemical Information

Catalog Num A10903
Actions Inhibitor
M. Wt 409.8
Formula C20H16ClN5O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 332012-40-5
Synonyms BAY57-9352
SMILES code CNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl
Chemical Name 4-[[[4-[(4-Chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl]oxy]methyl]-N-methyl-2-pyridinecarboxamide

Biological Activity

Description
Telatinib (BAY 57-9352) is an orally available, small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3) and platelet-derived growth factor receptor β tyrosine kinases.
Targets
c-Kit VEGFR3 VEGFR2 PDGFRα
1 nM4 nM6 nM15 nM

Solubility

Solubility (25°C)* In vitro DMSO 82 mg/mL (200.08 mM)
Water <1 mg/mL (<1 mM)
Ethanol 1 mg/mL (2.44 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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