ZM 306416 hydrochloride

VEGFR Inhibitor

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Catalog No. A11955

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
ZM 306416 hydrochloride 10mg A11955-10
$90.00
ZM 306416 hydrochloride 25mg A11955-25
$180.00
ZM 306416 hydrochloride 50mg A11955-50
$300.00
ZM 306416 hydrochloride 100mg A11955-100
$500.00
ZM 306416 hydrochloride 10mM * 1mL in DMSO A11955-10mM-D
$92.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

ZM 306416 is a VEGF receptor tyrosine kinase inhibitor that inhibits KDR (IC50 = 100 nM) and Flt (IC50 = 2 uM) tyrosine kinases.

ZM 306416 hydrochloride

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Chemical Information

Catalog Num A11955
Actions Inhibitor
M. Wt 370.21
Formula C16H13N3O2FCl.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 690206-97-4
Synonyms ZM-306416
SMILES code COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC
Chemical Name 4-[(4'-Chloro-2'-fluoro)phenylamino]-6,7-dimethoxyquinazoline hydrochloride

Biological Activity

Description
ZM 306416 is a VEGF receptor tyrosine kinase inhibitor that inhibits KDR (IC50 = 100 nM) and Flt (IC50 = 2 uM) tyrosine kinases.
Targets
VEGFR1 Src Abl
0.33 μM0.33 μM1.3 μM

Solubility

Solubility (25°C)* In vitro DMSO 67 mg/mL (200.75 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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