Abiraterone Acetate (CB7630)

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CYP17 inhibitor

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Catalog No. A11058

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Abiraterone Acetate 5mg A11058-5

Regular Price: $30.00

Special Price: $25.50

Abiraterone Acetate 10mg A11058-10

Regular Price: $50.00

Special Price: $42.50

Abiraterone Acetate 50mg A11058-50

Regular Price: $60.00

Special Price: $51.00

Abiraterone Acetate 100mg A11058-100

Regular Price: $80.00

Special Price: $68.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Abiraterone acetate (CB7630) is an orally active acetate ester of the steroidal compound Abiraterone with antiandrogen activity. Abiraterone inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1).

Abiraterone Acetate (CB7630)

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Chemical Information

Catalog Num A11058
Actions Inhibitor
M. Wt 391.3
Formula C26H33NO2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 154229-18-2
Synonyms CB-7630
SMILES code CC(=O)O[[email protected]]1CC[[email protected]@]2([[email protected]]3CC[[email protected]]4([[email protected]]([[email protected]@H]3CC=C2C1)CC=C4C5=CN=CC=C5)C)C
Chemical Name (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol acetate

Biological Activity

Description
Abiraterone acetate (CB7630) is an orally active acetate ester of the steroidal compound Abiraterone with antiandrogen activity. Abiraterone inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1).
Targets
CYP17 (Cell-free assay)
72 nM

Solubility

Solubility (25°C) * In vitro DMSO <1 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol 28 mg/mL (71.51 mM)
In vivo 5% DMSO/95% Corn oil 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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