ADX-47273

Catalog No.: A11181
mGluR5 modulator

ADX-47273 is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5.

Grouped product items
Product Name Price Stock Qty
ADX-47273 5mg
$50.00
In stock
ADX-47273 10mg
$80.00
In stock
ADX-47273 50mg
$290.00
In stock
ADX-47273 100mg
$520.00
In stock
ADX-47273 10mM * 1mL in DMSO
$55.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription

ADX-47273 is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5.

Targets
Target Value
Product Information
Catalog Num A11181
Formula C20H17F2N3O2
Molecular Weight 369.36
CAS Number 851881-60-2
SMILES C1C[C@@H](CN(C1)C(=O)C2=CC=C(C=C2)F)C3=NC(=NO3)C4=CC=C(C=C4)F
Synonyms ADX47273
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 73 mg/mL (197.63 mM)
Water Insoluble
Ethanol 29 mg/mL (78.51 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.07 mL 135.37 mL 270.74 mL
0.5 mM 5.41 mL 27.07 mL 54.15 mL
1 mM 2.71 mL 13.54 mL 27.07 mL
5 mM 0.54 mL 2.71 mL 5.41 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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