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SB 258585 HCl
Catalog No. A14026 5-HT6 serotonin receptor antagonistSB 258585 hydrochloride has been found to be a selective and potent SR-6 antagonist. This compound displays more than a 160-fold selectivity over other serotonin receptor subtypes. Learn More -
Granisetron
Catalog No. A15096 5-HT3 antagonistGranisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Learn More -
LY 344864
Catalog No. A15148 5HT1F agonistLY344864 is a selective receptor agonist with an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor. Learn More -
WAY-100635 maleate salt
Catalog No. A15282 5HT1A antagonistWAY-100635 maleate is a potent and selective 5-hydroxytryptamine1A antagonist with an IC50 of 0.95 - 0.12 nM for 5-HT. Learn More -
Piboserod
Catalog No. A15542 5-HT4 receptor antagonistPiboserod is a selective 5-HT(4) receptor antagonist. Learn More -
Ricasetron
Catalog No. A15499 5-HT3 receptor antagonistRicasetron is a drug which acts as a selective antagonist at the serotonin 5-HT3 receptor. Learn More -
LY278584
Catalog No. A15500 5-HT3 antagonistLY278584 is a potent and selective antagonist of 5-HT3 receptors. LY278584 is a useful ligand for studying the localization of 5-HT3 receptors in rat brain Learn More -
Lerisetron
Catalog No. A15501 5HT3 receptor antagonistLerisetron is a serotonin type 3 (5-HT3) receptor antagonist with antiemetic activity. Learn More -
SB271046
Catalog No. A15438 5-HT Receptor AntagonistSB271046 is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9, exhibits 200-fold greater selectivity over other 5-HT receptor subtypes. Learn More -
Pimavanserin (ACP-103)
Catalog No. A14434 5-HT2A receptor agonistPimavanserin is a potent and selective 5-HT2A receptor inverse agonist with mean pIC50 of with 8.7 in the cell-based functional assay. Learn More -
Ketanserin tartrate
Catalog No. A13664 5HT2A antagonistKetanserin tartrate is a salt of Ketanserin. Ketanserin is reported to have a high affinity for multiple G protein-coupled receptors, such as serotonin receptors. Learn More -
WAY 181187
Catalog No. A14163 5-HT6 agonistWAY 181187 is a high affinity and selective 5-HT6 agonist with Ki value of 2.2 nM. Learn More -
GSK163090
Catalog No. A15838 5-HT1A/B/D receptor antagonistGSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist with pKi of 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3, respectively. Learn More -
Flopropione
Catalog No. A16550 5-HT1A receptor antagonist/COMT inhibitorFlopropione is a 5-HT1A receptor antagonist and also a catechol-o-methyltransferase (COMT) inhibitor. Learn More -
MHP 133
Catalog No. A20058 AChE /M1/M2/5HT4/I2 inhibitorMHP 133 is a drug with multiple CNS targets, and inhibits acetylcholinesterase (AChE) with Ki of 69 μM; also active against muscarinic M1 and M2 receptors, serotonin 5HT4 receptors, and imidazole I2 receptors. Learn More -
CP-809101
Catalog No. A12481 5-HT2C receptor agonistCP-809101 is a potent and selective 5-HT2C receptor agonist with pEC50 of 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors respectively. Learn More -
Donitriptan
Catalog No. A13145 5-HT1B/1D receptors agonistDonitriptan is a potent, high efficacy agonist at 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively. Learn More -
Deramciclane
Catalog No. A13011 5-HT2A and 5-HT2C receptors antagonistDeramciclane has a high affinity for 5-HT2A and 5-HT2C receptors; it acts as an antagonist at both receptor subtypes and has inverse agonist properties at the 5-HT2C receptors without direct stimulatory agonist. Learn More -
YM348
Catalog No. A12290 5-HT2C receptor agonistYM348 is a potent and orally active 5-HT2C receptor agonist, which shows a high affinity for cloned human 5-HT2C receptor (Ki: 0.89 nM). Learn More -
AP521
Catalog No. A12280 human 5-HT1A receptor agonistAP521 is an agonist of human 5-HT1A receptor with an IC50 of 94 nM. Learn More -
lumateperone Tosylate
Catalog No. A12279 5-HT2A receptor antagonistLumateperone Tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a SERT blocker (Ki = 61 nM). Learn More -
5-HT4 antagonist 1
Catalog No. A12268 5-HT4 receptor antagonist5-HT4 antagonist 1 is a 5-HT4 receptor antagonist with a pKi of 9.6. Learn More -
PRX933 hydrochloride
Catalog No. A12261 5-HT2c receptor agonistPRX933 hydrochloride is a 5-HT2c receptor agonist extracted from patent WO 2014140631 A1. Learn More -
Ziprasidone hydrochloride monohydrate
Catalog No. A11008 5-HT (serotonin) and dopamine receptor antagonistZiprasidone hydrochloride monohydrate (CP 88059 hydrochloride monohydrate) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. Learn More -
Pancopride
Catalog No. A12967 5-HT3 receptor antagonistPancopride is a new potent and selective 5-HT3 receptor antagonist. Learn More -
Lesopitron dihydrochloride
Catalog No. A12950 5-HT1A receptor agonistLesopitron dihydrochloride is a full and selective 5-HT1A receptor agonist with IC50 of 125 nM in rat hippocampal membranes. Learn More -
SB 271046 Hydrochloride
Catalog No. A11573 5-HT6 receptor antagonistSB271046 Hydrochloride is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9. Learn More -
WAY-100635 Maleate
Catalog No. A16787 5-HT1A receptor antagonistWAY-100635 maleate is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 value of 0.91 nM and Ki value of 0.39 nM. Learn More -
Ziprasidone hydrochloride
Catalog No. A16790 5-HT (serotonin)/dopamine receptor antagonistZiprasidone Hcl(CP-88059 Hcl) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. Learn More -
Sarpogrelate hydrochloride
Catalog No. A17295 5-HT2 antagonistSarpogrelate hydrochloride (MCI-9042), a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. Learn More -
RU 24969
Catalog No. A20857 5-HT1A/5-HT1B receptors agonistRU 24969 is a selective agonist at the 5-HT1A and 5-HT1B receptors. Learn More -
Befiradol
Catalog No. A21189 5-HT1A receptor agonistBefiradol (NLX-112) is a selective 5-HT1A receptor agonist. Learn More -
RS 127445
Catalog No. A21256 5-HT2B receptor antagonistRS 127445 is a novel high affinity, selective 5-HT2B receptor antagonist with pKi of 9.5. Learn More -
Vortioxetine
Catalog No. A21266 5-HT1A/5-HT1B/5-HT3A/5-HT7 receptor/SERT inhibitorVortioxetine is a inhibitor of 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT, with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. Learn More -
WAY 163909
Catalog No. A21282 5-HT(2C) receptor agonistWAY 163909 is a potent and selective 5-HT(2C) receptor agonist with a Ki of 10.5??1.1 nM. Learn More -
SB 242084 Dihydrochloride
Catalog No. A21349 5-HT2C receptor antagonistSB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively. Learn More -
Masupirdine mesylate
Catalog No. A21409 5-HT6 receptor antagonistMasupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist (Ki of 2.04 nM for human 5-HT6 receptor). Learn More -
Nelotanserin
Catalog No. A21506 5-HT2A inverse agonistNelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively. Learn More -
SB 242084
Catalog No. A21715 5-HT2C receptor antagonistSB 242084 is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively. Learn More -
LY 344864 S-enantiomer
Catalog No. A21742 5-HT1F receptor agonistLY 344864 S-enantiomer is the S-enantiomer of LY344864. LY344864 is a 5-HT1F receptor agonist. Learn More -
LY 344864 hydrochloride
Catalog No. A21748 5-HT1F agonistLY 344864 hydrochloride is a selective 5-HT1F agonist with a Ki of 6 nM. Learn More -
Vilazodone D8
Catalog No. A21876 SSR inhibitor / 5-HT1A receptor partial agonistVilazodone D8 is the a deuterium labeled vilazodone, which is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist. Learn More -
SB-269970 hydrochloride
Catalog No. A21889 5-HT7 receptor antagonistSB269970 hydrochloride (SB-269970A) is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with the pKi of 8.3, exhibits >50-fold selectivity against other receptors. Learn More -
SB-224289 hydrochloride
Catalog No. A21920 5-HT1B receptor antagonistSB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect. Learn More -
Ritanserin
Catalog No. A21976 5-HT2 receptor antagonistRitanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors. Learn More -
Eplivanserin mixture
Catalog No. A21987 serotonin reuptake inhibitor/5-HT2A receptor antagonistEplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist, extracted from patent WO 2005/002578 A1. Learn More -
Ziprasidone D8
Catalog No. A21989 5-HT / dopamine receptor antagonistZiprasidone D8 is deuterium labeled Ziprasidone, which is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. Learn More -
Aripiprazole (D8)
Catalog No. A22004 human 5-HT1A receptor partial agonistAripiprazole D8 (OPC-14597 D8) is the deuterium labeled Aripiprazole, which is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM. Learn More -
Mosapride citrate
Catalog No. A10607 5-HT4-receptor agonistMosapride citrate acts as 5-HT4 receptor agonist and 5-HT3 receptor antagonist. Learn More -
Tianeptine sodium
Catalog No. A10931 5-HT Receptor agonistTianeptine sodium is a selective serotonin reuptake enhancer (SSRE) in vitro and in vivo. Learn More
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