AEE788

Catalog No.: A10043
EGFR inhibitor
AEE788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor that inhibits phosphorylation of the tyrosine kinases of EGFR, HER2 and VEGF2.
Grouped product items
Product Name Price Stock Qty
AEE788 5mg
$70.00
In stock
AEE788 10mg
$120.00
In stock
AEE788 25mg
$220.00
In stock
AEE788 50mg
$400.00
In stock
AEE788 10mM * 1mL in DMSO
$165.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription AEE788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor that inhibits phosphorylation of the tyrosine kinases of EGFR, HER2 and VEGF2.
Targets
Target Value
Product Information
Catalog Num A10043
Formula C27H32N6
Molecular Weight 440.6
CAS Number 497839-62-0
SMILES CCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(N3)N=CN=C4N[C@H](C)C5=CC=CC=C5
Synonyms NVP-AEE788
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 81 mg/mL (183.84 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.7 mL 113.48 mL 226.96 mL
0.5 mM 4.54 mL 22.7 mL 45.39 mL
1 mM 2.27 mL 11.35 mL 22.7 mL
5 mM 0.45 mL 2.27 mL 4.54 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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