AV-412

Catalog No.: A11028
EGFR inhibitor
AV-412 is an EGFR/HER2 inhibitor that binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis.
Grouped product items
Product Name Price Stock Qty
AV-412 2mg
$60.00
In stock
AV-412 5mg
$99.00
In stock
AV-412 10mg
$165.00
In stock
AV-412 50mg
$495.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's AV-412 has been cited by 1 publications
  • Le Zhang, .et al. , Oncotarget, 2016, Apr 12; 7(15): 19948-19959 PMID: 26942566
  • Biological Activity
    Discription AV-412 is an EGFR/HER2 inhibitor that binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis.
    Targets
    Target Value
    Product Information
    Catalog Num A11028
    Formula C27H28ClFN6O.2C7H8O3S
    Molecular Weight 851.4
    CAS Number 451493-31-5
    SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CC(C)(C#CC1=CC2=C(C=C1NC(=O)C=C)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)N4CCN(CC4)C
    Synonyms AV412, MP-412
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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