Avasimibe (CI-1011)

Avasimibe (CI-1011) is an orally bioavailable Acyl-CoA:Cholesterol O-Acyltransferase (ACAT) inhibitor.
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Product Name Price Stock Qty
Avasimibe 10mg
$50.00
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Avasimibe 50mg
$180.00
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Avasimibe 100mg
$320.00
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Avasimibe 200mg
$520.00
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Avasimibe (CI-1011) 10mM * 1mL in DMSO
$84.00
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Adooq Products cited in reputable paper
Adooq's Avasimibe (CI-1011) has been cited by 1 publications
  • Yuyan Zhu, .et al. , Metabolism, 2021, Oct;123:154861 PMID: 34371065
  • Biological Activity
    Discription Avasimibe (CI-1011) is an orally bioavailable Acyl-CoA:Cholesterol O-Acyltransferase (ACAT) inhibitor.
    Targets
    Target Value
    Product Information
    Catalog Num A10102
    Formula C29H43NO4S
    Molecular Weight 501.7
    CAS Number 166518-60-1
    SMILES CC(C)C1=C(C(=CC=C1)C(C)C)OS(=O)(=O)NC(=O)CC2=C(C=C(C=C2C(C)C)C(C)C)C(C)C
    Synonyms PD 148515
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 96 mg/mL (191.34 mM)
    Water Insoluble
    Ethanol 8 mg/mL (15.94 mM)
    In vivo 2% DMSO+corn oil 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.93 mL 99.66 mL 199.32 mL
    0.5 mM 3.99 mL 19.93 mL 39.86 mL
    1 mM 1.99 mL 9.97 mL 19.93 mL
    5 mM 0.4 mL 1.99 mL 3.99 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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