Avasimibe (CI-1011)
Avasimibe (CI-1011) is an orally bioavailable Acyl-CoA:Cholesterol O-Acyltransferase (ACAT) inhibitor.
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Adooq Products cited in reputable paper
Adooq's Avasimibe (CI-1011) has been cited by 1 publications
- Yuyan Zhu, .et al. , Metabolism, 2021, Oct;123:154861 PMID: 34371065
Biological Activity
| Description | Avasimibe (CI-1011) is an orally bioavailable Acyl-CoA:Cholesterol O-Acyltransferase (ACAT) inhibitor. | |||||
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| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A10102 |
|---|---|
| Formula | C29H43NO4S |
| Molecular Weight | 501.7 |
| CAS Number | 166518-60-1 |
| SMILES | CC(C)C1=C(C(=CC=C1)C(C)C)OS(=O)(=O)NC(=O)CC2=C(C=C(C=C2C(C)C)C(C)C)C(C)C |
| Synonyms | PD 148515 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 96 mg/mL (191.34 mM) | |
| Water | Insoluble | ||
| Ethanol | 8 mg/mL (15.94 mM) | ||
| In vivo | 2% DMSO+corn oil | 4 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.93 mL | 99.66 mL | 199.32 mL |
| 0.5 mM | 3.99 mL | 19.93 mL | 39.86 mL |
| 1 mM | 1.99 mL | 9.97 mL | 19.93 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.99 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
