Avasimibe (CI-1011) ON SALE CYP17 inhibitor

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Catalog No. A10102

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Avasimibe 10mg A10102-10

Regular Price: $50.00

Special Price: $42.50

Avasimibe 50mg A10102-50

Regular Price: $180.00

Special Price: $153.00

Avasimibe 100mg A10102-100

Regular Price: $320.00

Special Price: $272.00

Avasimibe 200mg A10102-200

Regular Price: $520.00

Special Price: $442.00

Avasimibe (CI-1011) 10mM * 1mL in DMSO A10102-10mM-D

Regular Price: $84.00

Special Price: $71.40

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Avasimibe (CI-1011) is an orally bioavailable Acyl-CoA:Cholesterol O-Acyltransferase (ACAT) inhibitor.

Avasimibe (CI-1011)

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Chemical Information

Catalog Num A10102
Actions Inhibitor
M. Wt 501.7
Formula C29H43NO4S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 166518-60-1
Synonyms CI-1011, CI1011, PD 148515
SMILES code CC(C)C1=C(C(=CC=C1)C(C)C)OS(=O)(=O)NC(=O)CC2=C(C=C(C=C2C(C)C)C(C)C)C(C)C
Chemical Name [[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl ester] sulfamic acid

Biological Activity

Avasimibe (CI-1011) is an orally bioavailable Acyl-CoA:Cholesterol O-Acyltransferase (ACAT) inhibitor.
2.9 μM3.3 μM13.9 μM26.5 μM


Solubility (25°C) * In vitro DMSO 100 mg/mL (199.31 mM
Water <1 mg/mL (<1 mM)
Ethanol 8 mg/mL (15.94 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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