AZ 3146

ON SALE

Mps1 inhibitor

0 Customer Reviews
Catalog No. A11170

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AZ 3146 5mg A11170-5

Regular Price: $50.00

Special Price: $42.50

AZ 3146 10mg A11170-10

Regular Price: $80.00

Special Price: $68.00

AZ 3146 50mg A11170-50

Regular Price: $240.00

Special Price: $204.00

AZ 3146 100mg A11170-100

Regular Price: $450.00

Special Price: $382.50

AZ 3146 10mM * 1mL in DMSO A11170-10mM-D

Regular Price: $90.00

Special Price: $76.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AZ 3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). It interferes with chromosome alignment and overrides spindle assembly checkpoint and also Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores.

AZ 3146

Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products

Chemical Information

Catalog Num A11170
Actions Inhibitor
M. Wt 452.55
Formula C24H32N6O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1124329-14-1
Synonyms AZ-3146
SMILES code CN1CCC(CC1)OC2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(C(=O)N4C)C5CCCC5)OC
Chemical Name 9-Cyclopentyl-2-[[2-methoxy-4-[(1-m ethylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7, 9-dihydro-8H-purin-8-one

Biological Activity

Description

AZ 3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). It interferes with chromosome alignment and overrides spindle assembly checkpoint and also Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores.

Targets
Mps1
~35 nM

Solubility

Solubility (25°C)* In vitro DMSO 28 mg/mL (61.87 mM)
Water <1 mg/mL (<1 mM)
Ethanol 91 mg/mL (201.08 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

View Related Products By Research Topics

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.


Keywords:buy AZ 3146 | AZ 3146 Supplier | purchase AZ 3146 | AZ 3146 cost | AZ 3146 manufacturer | order AZ 3146 | AZ 3146 distributor | buy 1124329-14-1| 1124329-14-1 Supplier | purchase 1124329-14-1 | 1124329-14-1 cost | 1124329-14-1 manufacturer | order 1124329-14-1 | 1124329-14-1 distributor