2018-2019 AdooQ Catalog Book Available Click here to download


Raf inhibitor

0 Customer Reviews
Catalog No. A11063

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AZ628 5mg A11063-5

Regular Price: $70.00

Special Price: $56.00

AZ628 10mg A11063-10

Regular Price: $110.00

Special Price: $88.00

AZ628 25mg A11063-25

Regular Price: $220.00

Special Price: $176.00

AZ628 50mg A11063-50

Regular Price: $360.00

Special Price: $288.00

AZ628 10mM * 1mL in DMSO A11063-10mM-D

Regular Price: $75.00

Special Price: $60.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AZ628 is a RAF inhibitor with IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF.


Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products

Chemical Information

Catalog Num A11063
Actions Inhibitor
M. Wt 451.5
Formula C27H25N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 878739-06-1
Synonyms AZ-628
SMILES code CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
Chemical Name 3-(1-Cyano-1-methylethyl)-N-[3-[(3,4-dihydro-3-methyl-4-oxo-6-quinazolinyl)amino]-4-methylphenyl]benzamide

Biological Activity

AZ628 is a RAF inhibitor with IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF.
C-Raf-1 (Cell-free assay) B-Raf (V600E) (Cell-free assay) B-Raf (Cell-free assay)
29 nM34 nM105 nM


Solubility (25°C) * In vitro DMSO 90 mg/mL (199.32 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

View Related Products By Research Topics

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Similar product(s)

Keywords:buy AZ628 | AZ628 Supplier | purchase AZ628 | AZ628 cost | AZ628 manufacturer | order AZ628 | AZ628 distributor | buy 878739-06-1| 878739-06-1 Supplier | purchase 878739-06-1 | 878739-06-1 cost | 878739-06-1 manufacturer | order 878739-06-1 | 878739-06-1 distributor