AZD7762

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Chk1 & Chk2 inhibitor

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Catalog No. A10113

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AZD7762 5mg A10113-5

Regular Price: $40.00

Special Price: $32.00

AZD7762 10mg A10113-10

Regular Price: $70.00

Special Price: $56.00

AZD7762 25mg A10113-25

Regular Price: $150.00

Special Price: $120.00

AZD7762 100mg A10113-100

Regular Price: $580.00

Special Price: $464.00

AZD7762 10mM * 1mL in DMSO A10113-10mM-D

Regular Price: $88.00

Special Price: $70.40

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AZD7762 is a potent ATP-competitive checkpoint kinase inhibitor that drives checkpoint abrogation and potentiates DNA-targeted therapies.

AZD7762

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Chemical Information

Catalog Num A10113
Actions Inhibitor
M. Wt 362.4
Formula C17H19FN4O2S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 860352-01-8
Synonyms AZD-7762
SMILES code C1C[C@@H](CNC1)NC(=O)C2=C(C=C(S2)C3=CC(=CC=C3)F)NC(=O)N
Chemical Name 5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide

Biological Activity

Description
AZD7762 is a potent ATP-competitive checkpoint kinase inhibitor that drives checkpoint abrogation and potentiates DNA-targeted therapies.
Targets
Chk1 (Cell-free assay) Chk2 (Cell-free assay)
5 nM<10 nM

Solubility

Solubility (25°C)* In vitro DMSO 50 mg/mL (137.96 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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