BI6727 (Volasertib)

BI6727 is a highly potent and selective polo-like kinase (PLK) 1 inhibitor (enzyme IC50 = 0.87 nM, EC50 = 11-37 nM on a panel of cancer cell lines).
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Product Name Price Stock Qty
BI6727 5mg
$75.00
In stock
BI6727 10mg
$139.00
In stock
BI6727 50mg
$450.00
In stock
BI6727 100mg
$750.00
In stock
BI6727 (Volasertib) 10mM * 1mL in DMSO
$152.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's BI6727 (Volasertib) has been cited by 1 publications
  • Xiaofei Xin, .et al. , ACS Appl Mater Interfaces, 2019, 2019 PMID: 30933478
  • Biological Activity
    Discription BI6727 is a highly potent and selective polo-like kinase (PLK) 1 inhibitor (enzyme IC50 = 0.87 nM, EC50 = 11-37 nM on a panel of cancer cell lines).
    Targets
    Target Value
    Product Information
    Catalog Num A10135
    Formula C34H50N8O3
    Molecular Weight 618.8
    CAS Number 755038-65-4
    SMILES CC[C@@H]1C(=O)N(C2=CN=C(N=C2N1C(C)C)NC3=C(C=C(C=C3)C(=O)NC4CCC(CC4)N5CCN(CC5)CC6CC6)OC)C
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 19 mg/mL (30.7 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 4% DMSO+corn oil 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 16.16 mL 80.8 mL 161.6 mL
    0.5 mM 3.23 mL 16.16 mL 32.32 mL
    1 mM 1.62 mL 8.08 mL 16.16 mL
    5 mM 0.32 mL 1.62 mL 3.23 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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