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GABAA antagonist

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Catalog No. A12590

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
(+)-Bicuculline 50mg A12590-50

Regular Price: $70.00

Special Price: $56.00

(+)-Bicuculline 100mg A12590-100

Regular Price: $90.00

Special Price: $72.00

(+)-Bicuculline 250mg A12590-250

Regular Price: $190.00

Special Price: $152.00

(+)-Bicuculline 500mg A12590-500

Regular Price: $350.00

Special Price: $280.00

(+)-Bicuculline 10mM * 1mL in DMSO A12590-10mM-D

Regular Price: $64.00

Special Price: $51.20

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

(+)-Bicuculline is a classical GABAA antagonist.


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Chemical Information

Catalog Num A12590
Actions Antagonist
M. Wt 367.36
Formula C20H17NO6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 485-49-4
Synonyms N/A
SMILES code CN1CCC2=CC3=C(C=C2[[email protected]]1[[email protected]]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3
Chemical Name [R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6?-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,?4-e]-1,3-benzodioxol-8(6H)-one

Biological Activity

(+)-Bicuculline is a classical GABAA antagonist.
GABAA receptor
2 μM


Solubility (25°C)* In vitro DMSO 73 mg/mL heating (198.72 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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