BRL-15572 dihydrochloride

Catalog No.: A11178
5-HT1D receptor antagonist

BRL-15572 is a selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types.

Grouped product items
Product Name Stock
BRL-15572 5mg
BRL-15572 10mg
BRL-15572 50mg
BRL-15572 100mg
BRL-15572 10mM * 1mL in DMSO
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Biological Activity
Discription

BRL-15572 is a selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types.

Targets
Target Value
Product Information
Catalog Num A11178
Formula C25H29Cl3N2O
Molecular Weight 479.87
CAS Number 193611-72-2
SMILES C1CN(CCN1CC(C(C2=CC=CC=C2)C3=CC=CC=C3)O)C4=CC(=CC=C4)Cl.Cl.Cl
Synonyms BRL15572, BRL 15572
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 89 mg/mL (185.46 mM)
Water Insoluble
Ethanol 37 mg/mL (77.1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 19 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.84 mL 104.19 mL 208.39 mL
0.5 mM 4.17 mL 20.84 mL 41.68 mL
1 mM 2.08 mL 10.42 mL 20.84 mL
5 mM 0.42 mL 2.08 mL 4.17 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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